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OWNERSHIP PROFILE

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 30 277.13 19.91 16,345,346
Mutual Fund 14 6.78 0.39 320,115
Insider 2 6.08 0.31 253,242

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 7 130.05 6.72 5,517,760
Sellers 189 -1,515.16 77.57 -63,672,885
Net -- -1,385.11 70.85 -58,155,125

Concentration

Value ($MM) % O/S Shares
Total Inst. 277.13 19.91 16,345,346
Top 10 Inst. 264.22 19.23 15,787,801
Top 20 Inst. 276.48 19.88 16,318,045
Top 50 Inst. 277.13 19.91 16,345,346

Style

Holders Value ($MM) % Inst Shares Shares
Growth 1 0.04 -- 1,866
Core Growth 1 0.04 -- 1,866
Index 1 4.50 0.23 187,377
Other 4 219.43 11.31 9,285,810
GARP 1 -- -- 17
Hedge Fund 2 123.83 6.38 5,240,176
VC/Private Equi 1 95.60 4.93 4,045,617
Value 2 0.30 0.04 31,483
Core Value 2 0.30 0.04 31,483

Location: Global Region

Holders % O/S Shares Share Change
North America 5 14.64 12,020,139 4,590,138
Europe 6 0.37 304,890 303,007

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Magnetar Capital Partners LP 5,214,176 6.35 5,214,176 11/1/18
Sanderling Ventures 4,045,617 4.93 -- 11/14/18
Pension Fund of the Christian Church 2,758,063 3.36 -624,615 12/31/17
Cambridge Isotope Laboratories Inc 2,000,000 2.44 2,000,000 9/29/17
Low (Philip S) 564,249 0.69 133,519 12/21/18
Sherman Michael A 310,270 0.38 114,913 12/21/18
Dodwell (Peter) 300,000 0.37 300,000 9/29/17
Moll (Peter) 214,000 0.26 214,000 9/29/17
Middleton (Frederick A) 194,049 0.24 -3,300 11/14/18
Assenagon Asset Management S.A. 187,377 0.23 187,377 12/31/18

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Invesco MSCI Emerging Markets ETF 187,377 0.23 187,377 10/31/18
AXA Rosenberg Global Small Cap Equity Alpha Fund 29,700 0.04 29,700 3/31/18
Tekla Healthcare Investors 29,210 0.04 29,210 9/30/18
Laffitte Dynamic Strategies 26,000 0.03 26,000 10/31/18
UBS (CH) Inst Fd 2-Eq Global Small Cap Passive II 16,955 0.02 -6,345 11/30/18
PHARMA /wHEALTH Fund 13,141 0.02 -2,100 7/31/18
BlackRock Small Cap Index VI Fund 8,630 0.01 -1,836 9/30/18
UBS (CH) Institutional Fund - Equities Global Small Cap Passive II 2,300 -- -2,000 11/30/18
Pacific Select PD Small-Cap Growth Index Portfolio 2,247 -- -- 9/30/18
HSBC GIF Economic Scale US Equity 1,866 -- -- 11/30/18

* Insider values reflect direct beneficial ownership.

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