Shareholder Tools

Ownership Profile

Shareholder Breakdown
Shareholder Holders Values ($) % O/S Shares
Institution 158 66 56.51 24,000,235
Mutual Fund 110 18 18.02 7,653,453
Institutional Shareholder Rotation
Shareholder Holders Values Change ($) % O/S Shares Change
Buyers 54 4.92 4.26 1,807,337
Sellers 56 -5.63 5.15 -2,186,855
Net -- -0.71 0.89 -379,518
Institutional Shareholder Concentration
Shareholder Values ($) % O/S Shares
Top 10 Inst. 46 39.34 16,706,350
Top 20 Inst. 54.19 46.35 19,685,480
Top 50 Inst. 62.58 53.62 22,774,582
Total Inst. 62.58 53.62 22,774,582
Institutional Shareholder Style
Shareholder Holders Values ($) % O/S Shares
Index 20 14 12.47 5,295,437
AggresGr 1 1 0.46 195,800
CoreGrowth 14 3 2.79 1,186,708
Growth 4 0 0.15 63,441
IncomeValue 1 0 0.23 99,224
Yield 2 0 0.00 809
BrokerDealer 19 2 1.73 733,635
GARP 19 14 12.78 5,426,923
HedgeFund 14 4 3.27 1,386,841
Specialty 1 0 0.01 2,645
VCPrivateEquity 1 11 8.35 3,545,617
CoreValue 13 1 0.94 398,841
DeepValue 8 1 0.56 238,665
Momentum 1 0 0.00 1,819
Top Holders: Institutional Investor
Holder Shares Held % O/S Shares Change Filing Date
Sanderling Ventures 3,545,617 8.35 0 03/10/2016
Fidelity Management & Research Company 3,484,410 8.20 23,670 12/31/2016
Pension Fund of the Christian Church 3,382,678 7.96 0 03/10/2016
BlackRock Institutional Trust Company, N.A. 1,797,189 4.23 -418,434 12/31/2016
The Vanguard Group, Inc. 1,486,339 3.50 32,961 12/31/2016
Pinnacle Associates Ltd. 821,543 1.93 -50,754 12/31/2016
JP Morgan Asset Management 683,175 1.61 -8,800 12/31/2016
State Street Global Advisors (US) 620,248 1.46 16,289 12/31/2016
Highland Capital Management, L.P. 461,561 1.09 -3,645 12/31/2016
Low (Philip S) 423,590 1.00 14,918 02/06/2017
Highland Capital Healthcare Advisors, L.P. 411,315 0.97 411,315 09/30/2016
Millennium Management LLC 401,900 0.95 -44,165 12/31/2016
Northern Trust Investments, Inc. 373,544 0.88 15,612 12/31/2016
D. E. Shaw & Co., L.P. 357,548 0.84 25,957 12/31/2016
California Public Employees' Retirement System 263,500 0.62 127,100 12/31/2016
Ellis (P Ron) 261,382 0.62 -13,528 06/24/2016
Geode Capital Management, L.L.C. 254,619 0.60 8,754 12/31/2016
RMB Capital Management, LLC 243,385 0.57 25,500 12/31/2016
OxFORD Asset Management 209,260 0.49 55,175 12/31/2016
TIAA Global Asset Management 202,677 0.48 6,496 12/31/2016
Bridgeway Capital Management, Inc. 195,800 0.46 0 12/31/2016
Middleton (Frederick A) 190,749 0.45 2,250 05/05/2016
Morgan Stanley & Co. LLC 177,476 0.42 160,499 12/31/2016
Highland Capital Management Fund Advisors, L.P. 174,750 0.41 94,750 06/30/2016
BlackRock Investment Management, LLC 159,176 0.37 0 12/31/2016
Sherman Michael A 154,649 0.36 27,466 02/06/2017
PanAgora Asset Management Inc. 136,134 0.32 0 12/31/2016
Employees Retirement System of Texas 136,000 0.32 0 12/31/2016
Dreman Value Management, L.L.C. 134,500 0.32 -10,800 09/30/2016
RBC Capital Markets Wealth Management 132,621 0.31 -9,025 12/31/2016
Susquehanna Financial Group, LLLP 116,057 0.27 93,120 12/31/2016
Charles Schwab Investment Management, Inc. 110,071 0.26 37,728 12/31/2016
Frigate Ventures L.P. 108,426 0.26 108,426 12/31/2016
Columbia Threadneedle Investments (US) 105,160 0.25 25,750 12/31/2016
Parametric Portfolio Associates LLC 102,875 0.24 73,667 12/31/2016
BNY Mellon Asset Management 99,224 0.23 -19,278 12/31/2016
Goldman Sachs & Company, Inc. 83,440 0.20 31,696 12/31/2016
Two Sigma Investments, LP 81,768 0.19 81,768 12/31/2016
California State Teachers Retirement System 78,259 0.18 -2,200 12/31/2016
J.P. Morgan Securities LLC 76,760 0.18 76,760 12/31/2016
Jacobs Levy Equity Management, Inc. 76,374 0.18 26,620 12/31/2016
Leamon (Christopher P) 61,067 0.14 14,918 02/06/2017
Bellevue Research, Inc. 58,000 0.14 0 11/30/2015
New York State Common Retirement Fund 54,171 0.13 0 12/31/2016
Bel Air Investment Advisors, LLC 54,053 0.13 0 12/31/2015
Renaissance Technologies LLC 50,100 0.12 -138,900 12/31/2016
Andriole (Michael T.) 50,000 0.12 50,000 02/20/2017
Morgan Stanley Wealth Management 45,434 0.11 -18,830 12/31/2016
Florida State Board of Administration 43,302 0.10 0 12/31/2016
Rhumbline Advisers Ltd. Partnership 42,706 0.10 -1,731 12/31/2016

Ownership data is provided by Thomson Reuters, a third party service, and Endocyte, Inc. does not maintain or provide information directly to this service.